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Lexiscan® (regadenoson) injection is a prescription medicine that goes into your blood by an IV (intravenous) line. It increases blood flow through the arteries of the heart during a cardiac nuclear stress test. Lexiscan is used when a patient cannot exercise adequately for a stress test.

Lexiscan is not for everyone.

Lexiscan should not be given to patients who have certain abnormal heart rhythms, unless they have a pacemaker.

Lexiscan can cause serious or fatal cardiac arrest, abnormal heart rhythms, or heart attack.

Allergic reactions can occur after Lexiscan injection.

Lexiscan may cause an increase or decrease in blood pressure, especially in patients with certain heart and blood disorders.

Tell your doctor if you:

• Have a heart or blood vessel disorder
• Have a respiratory disease, such as COPD (chronic obstructive pulmonary disease) or asthma, and what medicines you take for it.

• Have a history of seizures. Lexiscan can increase the risk of seizures

Lexiscan can cause stroke, which may be a result of an increase or decrease in blood pressure.

The most common side effects that occurred in clinical trials of Lexiscan include:

• Shortness of breath
• Nausea
• Headache
• Abdominal discomfort
• Flushing
• A metallic taste in the mouth
• Chest discomfort or chest pain
• Feeling hot
• Dizziness

These side effects began soon after receiving Lexiscan and went away in 15 to 30 minutes.

In the 12 hours before your heart scan:

• Do not have any food and drinks that have caffeine in them
• Do not take medicines that have caffeine, aminophylline, or theophylline in them

Ask your doctor if you should stop taking any medicines you usually take before the day of the test.

If you are nursing, be sure to pump and throw away breast milk for 10 hours after receiving Lexiscan.